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Scouse

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Read the abstract and some of the main body of the text. It's a study about cold acclimation in "isolated perfused rat hearts" and its effect on enzymes, fats and energy use.
These observations indicate that for physiological hypertrophy AMPK phosphorylation does not mediate the enhanced translocation of LPL to cardiac endothelium

So, not much use as a rebuff to Raven's assertion.


Raven is, however, quite wrong :)
 

rynnor

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Read the abstract and some of the main body of the text. It's a study about cold acclimation in "isolated perfused rat hearts" and its effect on enzymes, fats and energy use.


So, not much use as a rebuff to Raven's assertion.


Raven is, however, quite wrong :)

The paper is titled 'Cold acclimation induces physiological cardiac hypertrophy and increases assimilation of triacylglycerol metabolism through lipoprotein lipase'

I wasnt interested in the second part but the first part is the enlargement of the heart that I mentioned - cardiac hypertrophy.

If you read through it you can also find the stuff about pressure in the arteries around the heart - they just acclimated a bunch of rats to the cold and dissected them to see what changes it made.
 

Raven

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Not for short term exposure I am not, which is all we really get. If we still lived in mud huts or caves then yes, you would see physical change.
 

old.Tohtori

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Interesting debate, considering i meant not wearing a hoodie indoors so that it -feels- warmer when you dress up for the cold ;)
 

rynnor

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Not for short term exposure I am not, which is all we really get. If we still lived in mud huts or caves then yes, you would see physical change.

Even short term exposure can have nasty consequences - tons of people have heart attacks shovelling snow and the cold exposure is a part of that.
 

dysfunction

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It's more likely that they are fat bastards that watch tv all day and that is the only exercise they have had all year.
 

rynnor

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It's more likely that they are fat bastards that watch tv all day and that is the only exercise they have had all year.

No doubt theres an element of that - if you dont have a nice lightweight snow shovel its pretty serious exercise but the cold means your hearts working harder to begin with trying to keep the body warm.
 

sayward

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My thermostat is in the hall which is nicely 24degrees. The lounge is bloody freezing!
 

rynnor

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Just wondering when I'll get a text to collect the kids from school like I did on Monday now its settling again...
 

caLLous

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Had about 3 flakes this morning, now it's just torrential rain. :(

I want torrential snow. :(
 

soze

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I have the bathroom set to 24degrees and my Bedroom is set to 24 degrees between 7am and 10am the rest of the house is set low just so it is on and the pipes don't freeze :)

Also the next person at work who says they can't wait for it to snow will get a throat punch. Why the fuck do you wantto get stuck in the fucking office. Snow is shit the country can't cope with it.
 

Raven

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People building shitty "nu-build" houses and diverting footpaths so that I nearly get lost walking home from work.
 

Poag

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Departments either side of us sent home. Us? No you have to stay the full day, we dont care how/if you get home.
 

leggy

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People who respond to an argument or criticism with: "you do that too!"
 

TdC

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lies: I'm not wearing my mustard-yellow cordoroy pants today
 

Deebs

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Wanting to delete my FB account and finding out that it is used as a developer account for FH. Fucksake.
 

Gwadien

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Did you slip up and fall on your arse?
Few near slips ;)

You know the 'oooooooooooooooooooh shit' moments, not actually slipping over.

Enough to be seen, but enough to hide it with a casual walk
 

Deebs

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Few near slips ;)

You know the 'oooooooooooooooooooh shit' moments, not actually slipping over.

Enough to be seen, but enough to hide it with a casual walk
Yeh, did that just now walking to shops. So I pretended to slide and act like a kid (loved it really!)
 

Gwadien

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Yeh, did that just now walking to shops. So I pretended to slide and act like a kid (loved it really!)
my legs are burning though, weirdly enough, the rest of my body is still freezing cold, but my thighs, are on fire, I DONT LIKE IT.
 

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